SNPs in bone-related miRNAs are associated with the osteoporotic phenotype

Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteopo...

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Veröffentlicht in:Sci Rep
Hauptverfasser: De-Ugarte, Laura, Caro-Molina, Enrique, Rodríguez-Sanz, Maria, García-Pérez, Miguel Angel, Olmos, José M., Sosa-Henríquez, Manuel, Pérez-Cano, Ramón, Gómez-Alonso, Carlos, Del Rio, Luis, Mateo-Agudo, Jesús, Blázquez-Cabrera, José Antonio, González-Macías, Jesús, Pino-Montes, Javier del, Muñoz-Torres, Manuel, Diaz-Curiel, Manuel, Malouf, Jorge, Cano, Antonio, Pérez-Castrillon, José Luis, Nogues, Xavier, Garcia-Giralt, Natalia, Diez-Perez, Adolfo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428869/
https://ncbi.nlm.nih.gov/pubmed/28364128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00641-7
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