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Blocking the Nav1.8 channel in the left stellate ganglion suppresses ventricular arrhythmia induced by acute ischemia in a canine model

Left stellate ganglion (LSG) hyperactivity promotes ischemia induced ventricular arrhythmia (VA). Blocking the Nav1.8 channel decreases neuron activity. Therefore, the present study aimed to investigate whether blocking the Nav1.8 channel with its specific blocker A-803467 in the LSG reduces sympath...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yu, Lilei, Wang, Menglong, Hu, Dan, Huang, Bing, Zhou, Liping, Zhou, Xiaoya, Wang, Zhuo, Wang, Songyun, Jiang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428783/
https://ncbi.nlm.nih.gov/pubmed/28373696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00642-6
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