Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways

Chronic renal failure (CRF) is a major public health problem worldwide. Hydrogen sulfide (H(2)S) plays important roles in renal physiological and pathophysiological processes. However, whether H(2)S could protect against CRF in rats remains unclear. In this study, we found that H(2)S alleviated gent...

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Pubblicato in:Sci Rep
Autori principali: Wu, Dongdong, Luo, Ning, Wang, Lianqu, Zhao, Zhijun, Bu, Hongmin, Xu, Guoliang, Yan, Yongjun, Che, Xinping, Jiao, Zhiling, Zhao, Tengfu, Chen, Jingtao, Ji, Ailing, Li, Yanzhang, Lee, Garrick D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428696/
https://ncbi.nlm.nih.gov/pubmed/28352125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00557-2
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