Effect of FOLFIRINOX as second-line chemotherapy for metastatic pancreatic cancer after gemcitabine-based chemotherapy failure

BACKGROUND: This study aimed to determine the maximum tolerated dose (MTD), dose-limiting toxicity, and efficacy of second-line chemotherapy with FOLFIRINOX after gemcitabine (GEM)-based chemotherapy failure in metastatic pancreatic cancer (MPC). METHODS: We studied 18 histopathologically proven MPC...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Kobayashi, Noritoshi, Shimamura, Takeshi, Tokuhisa, Motohiko, Goto, Ayumu, Endo, Itaru, Ichikawa, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2017
Assuntos:
4500
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428587/
https://ncbi.nlm.nih.gov/pubmed/28489753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000006769
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