High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice.

Reduced circulating levels of alpha 1-antitrypsin (alpha 1 AT) are associated with certain alpha 1 AT genotypes and increased susceptibility to emphysema. Unfortunately, the amounts of alpha 1 AT that would be required for replacement therapy are beyond the capacity of plasma fractionation and mamma...

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Bibliografiske detaljer
Main Authors: Archibald, A L, McClenaghan, M, Hornsey, V, Simons, J P, Clark, A J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54285/
https://ncbi.nlm.nih.gov/pubmed/1695012
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