Epigenetically regulated Fibronectin leucine rich transmembrane protein 2 (FLRT2) shows tumor suppressor activity in breast cancer cells

To identify dysregulated genes by abnormal methylation and expression in breast cancer, we genome-wide analyzed methylation and expression microarray data from the Gene Expression Omnibus and the Cancer Genome Atlas database. One of the genes screened in silico, FLRT2, showed hypermethylation and do...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Bae, Hansol, Kim, Byungtak, Lee, Hyunkyung, Lee, Seungyeon, Kang, Han-Sung, Kim, Sun Jung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428463/
https://ncbi.nlm.nih.gov/pubmed/28325946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00424-0
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