Insights from engraftable immunodeficient mouse models of hyperinsulinaemia

Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1 (−/−)) suitable for engraftment with human-derived tissue xenografts, an...

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Publicado en:Sci Rep
Autores principales: Maugham, Michelle L., Thomas, Patrick B., Crisp, Gabrielle J., Philp, Lisa K., Shah, Esha T., Herington, Adrian C., Chen, Chen, Gregory, Laura S., Nelson, Colleen C., Seim, Inge, Jeffery, Penny L., Chopin, Lisa K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428450/
https://ncbi.nlm.nih.gov/pubmed/28352127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00443-x
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