Insights from engraftable immunodeficient mouse models of hyperinsulinaemia

Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1 (−/−)) suitable for engraftment with human-derived tissue xenografts, an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maugham, Michelle L., Thomas, Patrick B., Crisp, Gabrielle J., Philp, Lisa K., Shah, Esha T., Herington, Adrian C., Chen, Chen, Gregory, Laura S., Nelson, Colleen C., Seim, Inge, Jeffery, Penny L., Chopin, Lisa K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428450/
https://ncbi.nlm.nih.gov/pubmed/28352127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00443-x
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