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Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure

In the eye, intraocular pressure (IOP) is tightly regulated and its persistent increase leads to ocular hypertension and glaucoma. We have previously shown that trabecular meshwork (TM) cells might detect aqueous humor fluid shear stress via interaction of the extracellular matrix (ECM) protein coch...

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發表在:Sci Rep
Main Authors: Carreon, Teresia A., Castellanos, Aida, Gasull, Xavier, Bhattacharya, Sanjoy K.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428432/
https://ncbi.nlm.nih.gov/pubmed/28352076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00430-2
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