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Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure

In the eye, intraocular pressure (IOP) is tightly regulated and its persistent increase leads to ocular hypertension and glaucoma. We have previously shown that trabecular meshwork (TM) cells might detect aqueous humor fluid shear stress via interaction of the extracellular matrix (ECM) protein coch...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Carreon, Teresia A., Castellanos, Aida, Gasull, Xavier, Bhattacharya, Sanjoy K.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428432/
https://ncbi.nlm.nih.gov/pubmed/28352076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00430-2
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