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Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure

In the eye, intraocular pressure (IOP) is tightly regulated and its persistent increase leads to ocular hypertension and glaucoma. We have previously shown that trabecular meshwork (TM) cells might detect aqueous humor fluid shear stress via interaction of the extracellular matrix (ECM) protein coch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Carreon, Teresia A., Castellanos, Aida, Gasull, Xavier, Bhattacharya, Sanjoy K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428432/
https://ncbi.nlm.nih.gov/pubmed/28352076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00430-2
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