ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

Mutations in Fused in Sarcoma/Translocated in Liposarcoma (FUS) cause familial forms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by progressive axonal degeneration mainly affecting motor neurons. Evidence from transgenic mouse models suggests mutant forms of FUS...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Rep
Main Authors: Sama, Reddy Ranjith K., Fallini, Claudia, Gatto, Rodolfo, McKeon, Jeanne E., Song, Yuyu, Rotunno, Melissa S., Penaranda, Saul, Abdurakhmanov, Izrail, Landers, John E., Morfini, Gerardo, Brady, Scott T., Bosco, Daryl A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428330/
https://ncbi.nlm.nih.gov/pubmed/28273913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00091-1
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍