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Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC colonies
The undifferentiated state of human induced pluripotent stem cells (hiPSCs) depends on their cell–cell and cell–substrate adhesions. In this study, we report that exposure to botulinum hemagglutinin (HA), an E-cadherin function-blocking agent, selectively removed cells that deviated from the undiffe...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428320/ https://ncbi.nlm.nih.gov/pubmed/28273902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00083-1 |
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