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A Biologically-validated HCV E1E2 Heterodimer Structural Model

The design of vaccine strategies and the development of drugs targeting the early stages of Hepatitis C virus (HCV) infection are hampered by the lack of structural information about its surface glycoproteins E1 and E2, the two constituents of HCV entry machinery. Despite the recent crystal resoluti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Castelli, Matteo, Clementi, Nicola, Pfaff, Jennifer, Sautto, Giuseppe A., Diotti, Roberta A., Burioni, Roberto, Doranz, Benjamin J., Dal Peraro, Matteo, Clementi, Massimo, Mancini, Nicasio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428263/
https://ncbi.nlm.nih.gov/pubmed/28303031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00320-7
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