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Fgf21 regulates T-cell development in the neonatal and juvenile thymus

We have previously shown that Fibroblast growth factor 21 (Fgf21) is expressed in the thymus as well as in the liver. In line with this expression profile, Fgf21 was recently reported to protect against ageing-related thymic senescence by improving the function of thymic epithelial cells (TECs). How...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakayama, Yoshiaki, Masuda, Yuki, Ohta, Hiroya, Tanaka, Tomohiro, Washida, Miwa, Nabeshima, Yo-ichi, Miyake, Ayumi, Itoh, Nobuyuki, Konishi, Morichika
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428243/
https://ncbi.nlm.nih.gov/pubmed/28336912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00349-8
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