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Transcriptional Regulation of the Human Growth Hormone Receptor (hGHR) Gene V2 Promoter by Transcriptional Activators and Repressor

The V2 transcript is the major ubiquitously expressed human GH receptor (hGHR) mRNA in all tissues examined to date. In a previous investigation, we defined the V2 promoter as TATA-less and exhibiting many characteristics of a housekeeping gene promoter. We also demonstrated that its basal activity...

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Publicat a:Mol Endocrinol
Autors principals: Wei, Yuhong, Puzhko, Svetlana, Wabitsch, Martin, Goodyer, Cynthia Gates
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428159/
https://ncbi.nlm.nih.gov/pubmed/19116245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0190
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