N-Oleoyldopamine Enhances Glucose Homeostasis through the Activation of GPR119

G protein-coupled receptor 119 (GPR119) is largely restricted to pancreatic insulin-producing β-cells and intestinal glucagon-like peptide-1-producing L-cells. Synthetic agonists of this receptor elicit glucose-dependent release of these endocrine factors, thereby enhancing glycemic control. Oleoyle...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Chu, Zhi-Liang, Carroll, Chris, Chen, Ruoping, Alfonso, Jean, Gutierrez, Veronica, He, Hongmei, Lucman, Annette, Xing, Charles, Sebring, Kristen, Zhou, Jinyao, Wagner, Brandee, Unett, David, Jones, Robert M., Behan, Dominic P., Leonard, James
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2010
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428146/
https://ncbi.nlm.nih.gov/pubmed/19901198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0239
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