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Up-regulation of Siah1 by ethanol triggers apoptosis in neural crest cells through p38 MAPK-mediated activation of p53 signaling pathway
Seven in absentia homolog 1 (SIAH1) is one of the E3 ubiquitin ligases and plays a key role in regulating target protein degradation. This study was designed to test the hypothesis that Siah1 mediates ethanol-induced apoptosis in NCCs through p38 MAPK-mediated activation of the p53 signaling pathway...
Gorde:
| Argitaratua izan da: | Arch Toxicol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428080/ https://ncbi.nlm.nih.gov/pubmed/27270636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1746-3 |
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