Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis

Diet plays a crucial role in shaping human health and disease. Diets promoting obesity and insulin resistance can lead to severe metabolic diseases, while calorie-restricted (CR) diets can improve health and extend lifespan. In this work, we fed mice either a chow diet (CD), a 16 week high-fat diet...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Soltis, Anthony R., Motola, Shmulik, Vernia, Santiago, Ng, Christopher W., Kennedy, Norman J., Dalin, Simona, Matthews, Bryan J., Davis, Roger J., Fraenkel, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428070/
https://ncbi.nlm.nih.gov/pubmed/28282965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00267-9
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