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Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression

Like the nucleus, mitochondria contain their own DNA and recent reports provide accumulating evidence that also the mitochondrial DNA (mtDNA) is subjective to DNA methylation. This evidence includes the demonstration of mitochondria-localised DNA methyltransferases and demethylases, and the detectio...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: van der Wijst, Monique G. P., van Tilburg, Amanda Y., Ruiters, Marcel H. J., Rots, Marianne G.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428053/
https://ncbi.nlm.nih.gov/pubmed/28282966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00263-z
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