Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3

Hepatic glucose production (HGP) is required to maintain normoglycemia during fasting. Glucagon is the primary hormone responsible for increasing HGP; however, there are many additional hormone and metabolic factors that influence glucagon sensitivity. In this study we report that the bioactive lipi...

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Publicat a:Sci Rep
Autors principals: Taddeo, Evan P., Hargett, Stefan R., Lahiri, Sujoy, Nelson, Marin E., Liao, Jason A., Li, Chien, Slack-Davis, Jill K., Tomsig, Jose L., Lynch, Kevin R., Yan, Zhen, Harris, Thurl E., Hoehn, Kyle L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428006/
https://ncbi.nlm.nih.gov/pubmed/28273928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00210-y
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