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Robust Analysis of Fluxes in Genome-Scale Metabolic Pathways

Constraint-based optimization, such as flux balance analysis (FBA), has become a standard systems-biology computational method to study cellular metabolisms that are assumed to be in a steady state of optimal growth. The methods are based on optimization while assuming (i) equilibrium of a linear sy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: MacGillivray, Michael, Ko, Amy, Gruber, Emily, Sawyer, Miranda, Almaas, Eivind, Holder, Allen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427939/
https://ncbi.nlm.nih.gov/pubmed/28325918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00170-3
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