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Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection

The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susceptible to...

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書目詳細資料
發表在:Sci Rep
Main Authors: Birchenough, George M. H., Dalgakiran, Fatma, Witcomb, Luci A., Johansson, Malin E. V., McCarthy, Alex J., Hansson, Gunnar C., Taylor, Peter W.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427930/
https://ncbi.nlm.nih.gov/pubmed/28250440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00123-w
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