Grape seed proanthocyanidins prevent irradiation-induced differentiation of human lung fibroblasts by ameliorating mitochondrial dysfunction

Radiation-induced lung fibrosis (RILF) is a long-term adverse effect of curative radiotherapy. The accumulation of myofibroblasts in fibroblastic foci is a pivotal feature of RILF. In the study, we found the inhibitory effect of grape seed proanthocyanidins (GSPs) on irradiation-induced differentiat...

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Published in:Sci Rep
Main Authors: Yang, XiaoHong, Liu, Tao, Chen, Bo, Wang, Fangqin, Yang, Qunfang, Chen, XiaoHong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427826/
https://ncbi.nlm.nih.gov/pubmed/28246402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00108-9
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