Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

BACKGROUND: Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity. We hypothesize that serum cathelicidin correlates with mucosal disease activity, stricture, and c...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Tran, Diana Hoang-Ngoc, Wang, Jiani, Ha, Christina, Ho, Wendy, Mattai, S. Anjani, Oikonomopoulos, Angelos, Weiss, Guy, Lacey, Precious, Cheng, Michelle, Shieh, Christine, Mussatto, Caroline C., Ho, Samantha, Hommes, Daniel, Koon, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427565/
https://ncbi.nlm.nih.gov/pubmed/28494754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-017-0619-4
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