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Complement component C3 - The “Swiss Army Knife” of innate immunity and host defense

As a preformed defense system, complement faces a delicate challenge in providing an immediate, forceful response to pathogens even at first encounter, while sparing host cells in the process. For this purpose, it engages a tightly regulated network of plasma proteins, cell surface receptors, and re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Rev
Hauptverfasser: Ricklin, Daniel, Reis, Edimara S., Mastellos, Dimitrios C., Gros, Piet, Lambris, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427221/
https://ncbi.nlm.nih.gov/pubmed/27782325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12500
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