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Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis

Biotin synthetic pathways are readily separated into two stages, synthesis of the seven carbon α, ω-dicarboxylic acid pimelate moiety and assembly of the fused heterocyclic rings. The biotin pathway genes responsible for pimelate moiety synthesis vary widely among bacteria whereas the ring synthesis...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Microbiol
Hauptverfasser: Manandhar, Miglena, Cronan, John E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426962/
https://ncbi.nlm.nih.gov/pubmed/28196402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13648
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