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Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells
Apicobasolateral polarity is a fundamental property of epithelial cells, and its loss is a hallmark of cancer. Integrin-mediated contact with the extracellular matrix defines the basal surface, setting in motion E-cadherin–mediated cell–cell contact, which establishes apicobasolateral polarity. Role...
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| Publicado en: | Mol Biol Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Cell Biology
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5426844/ https://ncbi.nlm.nih.gov/pubmed/28356422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0852 |
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