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The Challenges of Recombinant Endostatin in Clinical Application: Focus on the Different Expression Systems and Molecular Bioengineering

Angiogenesis plays an essential role in rapid growing and metastasis of the tumors. Inhibition of angiogenesis is a putative strategy for cancer therapy. Endostatin (Es) is an attractive anti-angiogenesis protein with some clinical application challenges including; short half-life, instability in se...

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Bibliografiske detaljer
Udgivet i:Adv Pharm Bull
Main Authors: Mohajeri, Abbas, Sanaei, Sarvin, Kiafar, Farhad, Fattahi, Amir, Khalili, Majid, Zarghami, Nosratollah
Format: Artigo
Sprog:Inglês
Udgivet: Tabriz University of Medical Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426730/
https://ncbi.nlm.nih.gov/pubmed/28507934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2017.004
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