Nasal airway epithelial cell IL-6 and FKBP51 gene expression and steroid sensitivity in asthmatic children

BACKGROUND: Many asthmatic patients exhibit uncontrolled asthma despite high-dose inhaled corticosteroids (ICS). Airway epithelial cells (AEC) have distinct activation profiles that can influence ICS response. OBJECTIVES: A pilot study to identify gene expression markers of AEC dysfunction and marke...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fayon, Michael, Lacoste-Rodrigues, Aurelie, Barat, Pascal, Helbling, Jean-Christophe, Nacka, Fabienne, Berger, Patrick, Moisan, Marie-Pierre, Corcuff, Jean-Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426685/
https://ncbi.nlm.nih.gov/pubmed/28493984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177051
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