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Inhibition of nitric oxide production reverses diabetes-induced Kupffer cell activation and Klebsiella pneumonia liver translocation

Klebsiella pneumoniae (KP) is the most common pathogen of pyogenic liver abscess in East and Southeast Asia and diabetes mellitus (DM) is a major risk factor. The effect and mechanism of diabetes on KP liver abscess was examined in streptozotocin-induced diabetic mice and Akita mice (C57BL/6J-Ins2(A...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Lin, Shu-Han, Chung, Pei-Hsuan, Wu, Ying-Ying, Fung, Chang-Phone, Hsu, Ching-Mei, Chen, Lee-Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426676/
https://ncbi.nlm.nih.gov/pubmed/28493939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177269
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