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Selective pre-priming of HA-specific CD4 T cells restores immunological reactivity to HA on heterosubtypic influenza infection

A hallmark of the immune response to influenza is repeated encounters with proteins containing both genetically conserved and variable components. Therefore, the B and T cell repertoire is continually being remodeled, with competition between memory and naïve lymphocytes. Our previous work using a m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Alam, Shabnam, Chan, Cory, Qiu, Xing, Shannon, Ian, White, Chantelle L., Sant, Andrea J., Nayak, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426616/
https://ncbi.nlm.nih.gov/pubmed/28493882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176407
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