In Silico Model-driven Assessment of the Effects of Brain-derived Neurotrophic Factor Deficiency on Glutamate and Gamma-Aminobutyric Acid: Implications for Understanding Schizophrenia Pathophysiology

OBJECTIVE: Deficient brain-derived neurotrophic factor (BDNF) is one of the important mechanisms underlying the neuroplasticity abnormalities in schizophrenia. Aberration in BDNF signaling pathways directly or circuitously influences neurotransmitters like glutamate and gamma-aminobutyric acid (GABA...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Psychopharmacol Neurosci
Hauptverfasser: Agrawal, Rimjhim, Kalmady, Sunil Vasu, Venkatasubramanian, Ganesan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean College of Neuropsychopharmacology 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426484/
https://ncbi.nlm.nih.gov/pubmed/28449558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9758/cpn.2017.15.2.115
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