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Quantitative assessment of Wilms tumor 1 expression by real-time quantitative polymerase chain reaction in patients with acute myeloblastic leukemia

BACKGROUND: The Wilms tumor 1 (WT1) gene is originally defined as a tumor suppressor gene and a transcription factor that overexpressed in leukemic cells. It is highly expressed in more than 80% of acute myeloid leukemia (AML) patients, both in bone marrow (BM) and in peripheral blood (PB), and it i...

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Vydáno v:J Res Med Sci
Hlavní autoři: Ayatollahi, Hossein, Sadeghian, Mohammad Hadi, Naderi, Mahmood, Jafarian, Amir Hossein, Shams, Seyyede Fatemeh, Motamedirad, Neda, Sheikhi, Maryam, Bahrami, Afsane, Shakeri, Sepideh
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426094/
https://ncbi.nlm.nih.gov/pubmed/28567073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/jrms.JRMS_448_16
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