載入...
Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
To study the physiological roles of NADH and NADPH homeostasis in cancer, we studied the effect of NNT knockdown on physiology of SK-Hep1 cells. NNT knockdown cells show limited abilities to maintain NAD(+) and NADPH levels and have reduced proliferation and tumorigenicity. There is an increased dep...
Na minha lista:
| 發表在: | Redox Biol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5426036/ https://ncbi.nlm.nih.gov/pubmed/28478381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.035 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|