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Intercalators promote the binding of RecA protein to double-stranded DNA.

Ethidium bromide, acridine orange, 4'-(9-acridinylamino)methanesulfon-o-anisidide (o-AMSA), and m-AMSA induce the rapid binding of RecA protein to double-stranded (ds) DNA. The filaments formed appear to retain the drug and are 12.8 nm in diameter with an 8.0-nm pitch. Two classes of drugs have...

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Bibliografiske detaljer
Main Authors: Thresher, R J, Griffith, J D
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC54260/
https://ncbi.nlm.nih.gov/pubmed/2195545
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