In Vitro Evaluations and In Vivo Toxicity and Efficacy Studies of MFM501 against MRSA

Previously we have discovered a synthetically derived pyrrolidone alkaloid, MFM501, exhibiting good inhibitory activity against 53 MRSA and MSSA isolates with low cytotoxicity against three normal cell-lines with IC(50) values at >625 µg/ml. Time-kill assay, scanning electron microscopy (SEM) ana...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Johari, Saiful Azmi, Mohtar, Mastura, Syed Mohamad, Sharifah Aminah, Mohammat, Mohd Fazli, Sahdan, Rohana, Mohamed, Azman, Mohamad Ridhwan, Mohamad Jemain
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425839/
https://ncbi.nlm.nih.gov/pubmed/28536702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8032865
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