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The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity

We argue that dynamic changes in DNA supercoiling in vivo determine both how DNA is packaged and how it is accessed for transcription and for other manipulations such as recombination. In both bacteria and eukaryotes, the principal generators of DNA superhelicity are DNA translocases, supplemented i...

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Bibliografske podrobnosti
izdano v:Biophys Rev
Main Authors: Muskhelishvili, Georgi, Travers, Andrew
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425797/
https://ncbi.nlm.nih.gov/pubmed/28510220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-016-0237-3
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