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The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity

We argue that dynamic changes in DNA supercoiling in vivo determine both how DNA is packaged and how it is accessed for transcription and for other manipulations such as recombination. In both bacteria and eukaryotes, the principal generators of DNA superhelicity are DNA translocases, supplemented i...

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Bibliografiske detaljer
Udgivet i:Biophys Rev
Main Authors: Muskhelishvili, Georgi, Travers, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425797/
https://ncbi.nlm.nih.gov/pubmed/28510220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-016-0237-3
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