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The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity

We argue that dynamic changes in DNA supercoiling in vivo determine both how DNA is packaged and how it is accessed for transcription and for other manipulations such as recombination. In both bacteria and eukaryotes, the principal generators of DNA superhelicity are DNA translocases, supplemented i...

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Detalhes bibliográficos
Publicado no:Biophys Rev
Main Authors: Muskhelishvili, Georgi, Travers, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425797/
https://ncbi.nlm.nih.gov/pubmed/28510220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-016-0237-3
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