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The regulatory role of DNA supercoiling in nucleoprotein complex assembly and genetic activity

We argue that dynamic changes in DNA supercoiling in vivo determine both how DNA is packaged and how it is accessed for transcription and for other manipulations such as recombination. In both bacteria and eukaryotes, the principal generators of DNA superhelicity are DNA translocases, supplemented i...

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Vydáno v:Biophys Rev
Hlavní autoři: Muskhelishvili, Georgi, Travers, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425797/
https://ncbi.nlm.nih.gov/pubmed/28510220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-016-0237-3
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