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Molecular Counting with Localization Microscopy: A Bayesian Estimate Based on Fluorophore Statistics
Superresolved localization microscopy has the potential to serve as an accurate, single-cell technique for counting the abundance of intracellular molecules. However, the stochastic blinking of single fluorophores can introduce large uncertainties into the final count. Here we provide a theoretical...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425379/ https://ncbi.nlm.nih.gov/pubmed/28494949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.03.020 |
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