Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells

To identify vascular disruptor compounds (VDCs), this study utilized an in vivo zebrafish embryo vascular model in conjunction with a mouse endothelial cell model to screen a subset of the U.S. Environmental Protection Agency (EPA) ToxCast Phase I chemical inventory. In zebrafish, 161 compounds were...

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Библиографические подробности
Опубликовано в: :Reprod Toxicol
Главные авторы: McCollum, Catherine W., Vancells, Javier Conde, Hans, Charu, Vazquez-Chantada, Mercedes, Kleinstreuer, Nicole, Tal, Tamara, Knudsen, Thomas, Shah, Shishir S., Merchant, Fatima A., Finnell, Richard H., Gustafsson, Jan-Åke, Cabrera, Robert, Bondesson, Maria
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425326/
https://ncbi.nlm.nih.gov/pubmed/27838387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.11.005
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