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Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells

To identify vascular disruptor compounds (VDCs), this study utilized an in vivo zebrafish embryo vascular model in conjunction with a mouse endothelial cell model to screen a subset of the U.S. Environmental Protection Agency (EPA) ToxCast Phase I chemical inventory. In zebrafish, 161 compounds were...

詳細記述

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書誌詳細
出版年:Reprod Toxicol
主要な著者: McCollum, Catherine W., Vancells, Javier Conde, Hans, Charu, Vazquez-Chantada, Mercedes, Kleinstreuer, Nicole, Tal, Tamara, Knudsen, Thomas, Shah, Shishir S., Merchant, Fatima A., Finnell, Richard H., Gustafsson, Jan-Åke, Cabrera, Robert, Bondesson, Maria
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425326/
https://ncbi.nlm.nih.gov/pubmed/27838387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.11.005
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