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Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells
To identify vascular disruptor compounds (VDCs), this study utilized an in vivo zebrafish embryo vascular model in conjunction with a mouse endothelial cell model to screen a subset of the U.S. Environmental Protection Agency (EPA) ToxCast Phase I chemical inventory. In zebrafish, 161 compounds were...
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出版年: | Reprod Toxicol |
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主要な著者: | , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5425326/ https://ncbi.nlm.nih.gov/pubmed/27838387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.11.005 |
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