Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells

To identify vascular disruptor compounds (VDCs), this study utilized an in vivo zebrafish embryo vascular model in conjunction with a mouse endothelial cell model to screen a subset of the U.S. Environmental Protection Agency (EPA) ToxCast Phase I chemical inventory. In zebrafish, 161 compounds were...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Reprod Toxicol
Auteurs principaux: McCollum, Catherine W., Vancells, Javier Conde, Hans, Charu, Vazquez-Chantada, Mercedes, Kleinstreuer, Nicole, Tal, Tamara, Knudsen, Thomas, Shah, Shishir S., Merchant, Fatima A., Finnell, Richard H., Gustafsson, Jan-Åke, Cabrera, Robert, Bondesson, Maria
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425326/
https://ncbi.nlm.nih.gov/pubmed/27838387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.11.005
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires