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Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.
Cu,Zn superoxide dismutase (Cu,Zn-SOD; EC 1.15.1.1) is known to be inhibited slowly by H2O2. Using EPR and the spin traps 5,5-dimethyl-1-pyrroline 1-oxide (DMPO) and N-tert-butyl-alpha-phenylnitrone (PBN), we have shown that Cu,Zn-SOD catalyzes the formation of "free" .OH radicals from H2O...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1990
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC54250/ https://ncbi.nlm.nih.gov/pubmed/2164216 |
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