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A coordinated DNA damage response promotes adult quiescent neural stem cell activation

Stem and differentiated cells frequently differ in their response to DNA damage, which can determine tissue sensitivity. By exploiting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we show distinct responses to ionising radiation (IR) b...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Barazzuol, Lara, Ju, Limei, Jeggo, Penny A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424956/
https://ncbi.nlm.nih.gov/pubmed/28489848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001264
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