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A coordinated DNA damage response promotes adult quiescent neural stem cell activation

Stem and differentiated cells frequently differ in their response to DNA damage, which can determine tissue sensitivity. By exploiting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we show distinct responses to ionising radiation (IR) b...

詳細記述

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書誌詳細
出版年:PLoS Biol
主要な著者: Barazzuol, Lara, Ju, Limei, Jeggo, Penny A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424956/
https://ncbi.nlm.nih.gov/pubmed/28489848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001264
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