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Design of Surfactant Protein B Peptide Mimics Based on the Saposin Fold for Synthetic Lung Surfactants

Surfactant protein (SP)-B is a 79-residue polypeptide crucial for the biophysical and physiological function of endogenous lung surfactant. SP-B is a member of the saposin or saposin-like proteins (SAPLIP) family of proteins that share an overall three-dimensional folding pattern based on secondary...

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Publicat a:Biomed Hub
Autors principals: Walther, Frans J., Gordon, Larry M., Waring, Alan J.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424708/
https://ncbi.nlm.nih.gov/pubmed/28503550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000451076
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