Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

BACKGROUND: BCG vaccination provides incomplete protection against tuberculosis in infants. A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was designed to enhance the protective efficacy of BCG. We aimed to assess safety, immunogenicity, and efficacy of MVA85A against...

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Bibliografiske detaljer
Udgivet i:Lancet
Main Authors: Tameris, Michele D, Hatherill, Mark, Landry, Bernard S, Scriba, Thomas J, Snowden, Margaret Ann, Lockhart, Stephen, Shea, Jacqueline E, McClain, J Bruce, Hussey, Gregory D, Hanekom, Willem A, Mahomed, Hassan, McShane, Helen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424647/
https://ncbi.nlm.nih.gov/pubmed/23391465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(13)60177-4
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