Intravenous Administration of Substance P Attenuates Mechanical Allodynia Following Nerve Injury by Regulating Neuropathic Pain-Related Factors

This study aimed to investigate the analgesic effect of substance P (SP) in an animal model of neuropathic pain. An experimental model of neuropathic pain, the chronic constriction injury (CCI) model, was established using ICR mice. An intravenous (i.v.) injection of SP (1 nmole/kg) was administered...

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Bibliographische Detailangaben
Veröffentlicht in:Biomol Ther (Seoul)
Hauptverfasser: Chung, Eunkyung, Yoon, Tae Gyoon, Kim, Sumin, Kang, Moonkyu, Kim, Hyun Jeong, Son, Youngsook
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Applied Pharmacology 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424635/
https://ncbi.nlm.nih.gov/pubmed/27956715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.137
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