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Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors
Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which is commonly explained by steric hindrance caused by the β-arrestins that...
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| Publicado no: | Biomol Ther (Seoul) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Korean Society of Applied Pharmacology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5424633/ https://ncbi.nlm.nih.gov/pubmed/27956717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.193 |
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