Loss of Snf5 induces formation of an aberrant SWI/SNF complex

The SWI/SNF chromatin remodeling complex is highly conserved from yeast to human and aberrant SWI/SNF complexes contribute to human disease. The Snf5/SMARCB1/INI1 subunit of SWI/SNF is a tumor supressor frequently lost in pediatric rhabdoid cancers. We examined the effects of Snf5 loss on the compos...

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Foilsithe in:Cell Rep
Main Authors: Sen, Payel, Luo, Jie, Hada, Arjan, Hailu, Solomon G., Dechassa, Mekonnen Lemma, Persinger, Jim, Brahma, Sandipan, Paul, Somnath, Ranish, Jeff, Bartholomew, Blaine
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424545/
https://ncbi.nlm.nih.gov/pubmed/28249160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.017
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