Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation

AIM: Small GTPase Rac1 is a member of the Ras superfamily, which plays important roles in regulation of cytoskeleton reorganization, cell growth, proliferation, migration, etc. The aim of this study was to determine how a constitutively active Rac1b regulated cell proliferation and to investigate th...

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Gepubliceerd in:Acta Pharmacol Sin
Hoofdauteurs: Ying, Li, Li, Gang, Wei, Si-si, Wang, Hong, An, Pei, Wang, Xun, Guo, Kai, Luo, Xian-jin, Gao, Ji-min, Zhou, Qing, Li, Wei, Yu, Ying, Li, Yi-gang, Duan, Jun-li, Wang, Yue-peng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424477/
https://ncbi.nlm.nih.gov/pubmed/25544362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.115
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