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Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1
Cancer cells frequently have amplified centrosomes that must be clustered together to form a bipolar mitotic spindle, and targeting centrosome clustering is considered a promising therapeutic strategy. A high-content chemical screen for inhibitors of centrosome clustering identified Stattic, a Stat3...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5424153/ https://ncbi.nlm.nih.gov/pubmed/28474672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15289 |
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