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Selective inhibition of protein kinase C β(2) attenuates the adaptor P66(Shc)-mediated intestinal ischemia–reperfusion injury
Apoptosis is a major mode of cell death occurring during ischemia–reperfusion (I/R) induced injury. The p66(Shc) adaptor protein, which is mediated by PKCβ, has an essential role in apoptosis under oxidative stress. This study aimed to investigate the role of PKCβ(2)/p66(Shc) pathway in intestinal I...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5424109/ https://ncbi.nlm.nih.gov/pubmed/24722289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.131 |
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